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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Curr Eye Res. 2015 Nov 10;41(7):977–986. doi: 10.3109/02713683.2015.1083588

Table 1. Rate of decline and linearity of retinal structure, function and visual behavior at different concentrations of PQ.

Displayed are the slopes of the loss of structural (OCT), function (ERG a- and b-waves) and visual behavior (OKT) of the retina at various concentrations of PQ over the course of the three week time period, which indicate the rate of degeneration at each concentration (mm/week for OCT, µV/week for a-wave and b-wave, and cycles/deg/week for OKT). Lower values for the slope indicate less degeneration, while higher values indicate more degeneration. Also displayed is the coefficient of determination (r2), which is a measure of the predictability of the decline of retinal structure, function and visual behavior.

Concentration OCT A-wave B-wave OKT

Slope r2 Slope r2 Slope r2 Slope r2

0 mM −0.001 0.3927 −10.36 0.8375 6.68 0.2167 −0.0055 0.2553
0.2 mM −0.0037 0.9928 −15.89 0.77 −52.91 0.7387 −0.0246 0.8634
0.4 mM −0.0096 0.9743 −31.14 0.8386 −89.81 0.77 −0.0915 0.8844
0.6 mM −0.0142 0.9505 −42.31 0.9694 −94.09 0.9873 −0.1040 0.9389
0.8 mM −0.0163 0.9373 −45.72 0.8608 −110.53 0.9293 −0.1417 0.8596
1 mM −0.0194 0.9577 −50.09 0.9268 −101.94 0.8353 −0.1397 0.7144