. Author manuscript; available in PMC: 2016 Aug 23.

Published in final edited form as: Liver Int. 2013 Jun 19;33(9):1324–1331. doi: 10.1111/liv.12214

Table 4.

Multivariate logistic regression models predicting death/liver transplantation in patients with acute liver failure according to serum cytokine concentrations and treatment group.

Model	Cytokine/Treatment Group	P	Odds Ratio	95% CI	AUROC
Early Cytokines^*	IL-17	0.016	3.46	1.41-10.77	0.65
Early Cytokines^* + Treatment Group	IL-2	0.007	6.15	1.84-26.25	0.82
	IL-17	<0.001	7.42	2.51-27.59
	Placebo vs. NAC	0.007	5.00	1.64-16.67
Late Cytokines^*	IL-17	0.020	5.29	1.64-28.97	0.66
Late Cytokines^* + Treatment Group	IL-17	0.035	4.78	1.44-28.02	0.75
Late Cytokines^* + Treatment Group	Placebo vs. NAC	0.035	3.13	1.10-7.69	0.75

Cytokines entered into models were those associated with outcome in patients with ALF in either previous or the present study: IL-1b, IL-2, IL-6, IL-10, IL-17, TNFα, IFNγ.