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. Author manuscript; available in PMC: 2016 Sep 22.
Published in final edited form as: Prostate Cancer Prostatic Dis. 2016 Mar 1;19(2):202–208. doi: 10.1038/pcan.2016.5

Table 1.

Baseline characteristics of patients

Did not undergo
2yr Biopsy
Underwent 2 yr Biopsy p-value
Number of Patients, n (%) 1,599 (20) 6,463 (80) -
Baseline Age, mean (SD) 62.8 (6.3) 62.7 (6.0) -
<65, n (%) 924 (19) 3849 (81) 0.065
65-69, n (%) 407 (19) 1681 (81)
≥70, n (%) 268 (22) 933 (78)
Race, n (%) <0.001
White 1432 (19) 5911 (81)
Black 59 (32) 122 (68)
Other 107 (20) 430 (80)
Missing 1 (100) 0 (0)
Region, n (%) <0.001
North America 485 (23) 1596 (77)
Europe 929 (19) 3951 (81)
Other 185 (17) 916 (83)
Center Volume, n (%) <0.001
1st tertile (0-10 subjects) 614 (25) 1872 (75)
2nd tertile (11-25 subjects) 489 (18) 2271 (82)
3rd tertile (>25 subjects) 496 (18) 2320 (82)
BMI, n (%) 0.063
<25 394 (19) 1726 (81)
25-29.9 845 (20) 3333 (80)
≥30 324 (20) 1309 (80)
Missing 36 (27) 95 (70)
PSA, n (%) 0.026
1st tertile 551 (21) 2066 (79)
2nd tertile 501 (19) 2195 (81)
3rd tertile 540 (20) 2191 (80)
Missing 7 (39) 11 (61)
Prostate Volume, n (%) 0.004
1st tertile 533 (20) 2119 (80)
2nd tertile 503 (19) 2149 (81)
3rd tertile 528 (20) 2125 (80)
Missing 35 (33) 70 (67)
DRE, n (%) 0.032
Normal/enlarged 1535 (20) 6213 (80)
Abnormal 57 (19) 242 (81)
Missing 7 (47) 8 (53)
IPSS Score, n (%) 0.004
0-7 (“Mild”) 701 (19) 3066 (81)
8-19 (“Moderate”) 733 (20) 2840 (80)
20-35 (“Severe”) 91 (26) 258 (74)
Missing 74 (20) 299 (80)
# of Medications Reported, n (%) 0.041
No medications 507 (22) 1838 (78)
1-5 949 (19) 4077 (81)
6-10 139 (21) 527 (79)
>10 4 (16) 21 (84)
Diabetes Mellitus Reported, n (%) 0.070
No 1440 (20) 5933 (80)
Yes 159 (23) 529 (77)
Missing 0 (0) 1 (100)
Hypertension Reported, n (%) 0.780
No 989 (20) 3999 (80)
Yes 610 (20) 2469 (80)
Missing 0 (0) 2 (100)
CAD Reported, n (%) 0.644
No 1464 (20) 5946 (80)
Yes 135 (21) 515 (79)
Missing 0 (0) 2 (100)
Smoking Status, n (%) 0.214
Never 718 (19) 2971 (81)
Former 612 (19) 2540 (81)
Current 268 (22) 947 (78)
Missing 1 (17) 5 (83)
Reported Alcohol Use, n (%) 0.001
Non-drinker 471 (22) 1624 (78)
Moderate Drinker (0-7/wk) 705 (18) 3151 (82)
Heavy Drinker (>7/wk) 410 (20) 1653 (80)
Missing 13 (27) 35 (73)
FHx Prostate Cancer, n (%) 0.203
No 1410 (20) 5607 (80)
Yes 187 (18) 852 (82)
Missing 2 (33) 4 (67)
FHx Breast Cancer, n (%) 0.117
No 1424 (20) 5740 (80)
Yes 173 (19) 722 (81)
Missing 2 (67) 1 (33)

Abbreviations: BMI, body mass index (kg/m2); CAD, coronary artery disease; DRE, digital rectal exam; FHx, reported family history of; IPSS, International Prostate Symptom Score.

P-value (bold)=Bonferroni corrections applied for statistically significant P-values (P=0.05/18=0.003).

P-value (italics)=Nominally statistically significant P-values (P<0.05).

a

Pearson Chi2.