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SINE28 shows features of retrotransposition. (A) Schematic of (top) primate Alus are derived from 7SL RNA with a LINE1 recognized A-rich tail (adapted from Mills et al. [2007]) and (bottom) SINE3/AmnSINE1 in vertebrates with a 5S rRNA head and CR1 recognized tail (adapted from Kapitonov and Jurka [2003]). (B) An example of a SINE28 embedded in an otherwise intact TE in the human genome (MER5B).
