Table 2.

Antibody concentration (µg/mL) for pneumococcal serotypes 10A, 11A, 15B and 17F as measured by ELISA.

Parameter	Pneumococcal Serotype
	10A		11A		15B		17F
	Baseline	Post-vaccination*	Baseline	Post-vaccination	Baseline	Post-vaccination	Baseline	Post-vaccination
Geometric Mean Concentration (µg/mL)	0.7	6.5	1.0	4.3	1.8	14.7	0.4	5.1
95% Confidence Interval (CI)	0.6, 1.0	4.9, 8.7	0.8, 1.2	3.6, 5.1	1.4, 2.3	11.9, 18.3	0.3, 0.6	3.9, 6.5
Median	0.7	6.7	1.0	4.5	1.9	14.1	0.4	5.1
Mean GMC Fold-rise	9.0		4.5		8.4		11.5
95% CI	7.2, 11.2		3.8, 5.4		6.8, 10.3		8.9, 14.9
Median	9.9		4.0		9.1		12.3
Proportion of Subjects with ≥2 -fold rise from baseline (Mean)	90.4%		84.6%		88.5%		89.4%
95% CI	83.0, 95.3		76.2, 90.9		80.7, 93.9		81.9, 94.6

^*Post-vaccination refers to 1 month (i.e., 21 to 35 d) following vaccination with PPV23