Table 1.

Model parameters. The effects of model parameters B and r, i.e. functional tumor-associated vasculature and effector cell recruitment rate respectively, are investigated by a model sensitivity analysis.

Description	Parameter	Value	Units	Sources
Mitotic rate of tumor cells	${\displaystyle {\lambda }_M}$	1.34	${\displaystyle {\text{days}}^{-1}}$	53,60,61
Death rate of tumor cells	${\displaystyle {\lambda }_A}$	0.14	${\displaystyle {\text{days}}^{-1}}$	53,60,61
Characteristic nutrient diffusion length	${\displaystyle L_D}$	[0.2 – 0.3]	${\displaystyle \text{mm}}$	53,62-64
Killing rate of tumor cells by effectors	${\displaystyle c}$	0.03	${\displaystyle {\text{cells}}^{-1} {\text{days}}^{-1}}$	20,32,53,55
Tumor volume where effector recruitment rate is half-maximal	${\displaystyle K}$	2.72	${\displaystyle {\text{mm}}^3}$	20,32,55,66
Inactivation rate of effectors by tumor cells	${\displaystyle d_1}$	0.01	${\displaystyle {\text{mm}}^{-3} {\text{days}}^{-1}}$	20,32,55,66
Death rate of effectors	${\displaystyle d_0}$	0.37	${\displaystyle {\text{days}}^{-1}}$	20,32,65,66
Background rate of effector recruitment	${\displaystyle \sigma }$	0.13 × 105	${\displaystyle \text{cells} {\text{days}}^{-1}}$	20,32,55,66