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. 2016 Aug 18;9:5133–5142. doi: 10.2147/OTT.S111132

Table 1.

Relationship between PN, EGFR, and clinicopathological parameters in 83 ESCC patients

Characteristics n PN
EGFR
High Low P-value High Low P-value
Gender 0.130 0.112
 Male 47 30 17 34 13
 Female 36 17 19 20 16
Age (years) 0.411 0.649
 <60 26 13 13 16 10
 ≥60 57 34 23 38 19
Tumor length (cm) 0.044 0.052
 <5 68 35 33 41 27
 ≥5 15 12 3 13 2
Tumor location 0.334 0.285
 Upper 8 3 5 4 4
 Middle 44 25 19 28 16
 Low 31 19 12 22 9
Invasion depth 0.007 0.022
 pT1 8 1 7 2 6
 pT2 26 13 13 16 10
 pT3 49 33 16 36 13
Differentiation grade 0.003 0.322
 Well 18 4 14 9 9
 Moderate 51 33 18 36 15
 Poor 14 10 4 9 5
Venous invasion 0.010 0.066
 Yes 18 15 3 15 3
 No 65 32 33 39 26
Lymphatic metastasis 0.000 0.000
 Yes 47 35 12 39 8
 No 36 12 24 15 21
Stage 0.000 0.000
 I 16 3 13 4 12
 II 31 14 17 21 10
 III 36 30 6 30 6

Note: Bold P-values are statistically significant.

Abbreviations: PN, periostin; EGFR, epidermal growth factor receptor; ESCC, esophageal squamous cell carcinoma; pT, pathological T stage.