Table 2. HIV incidence, unadjusted and adjusted factors associated with HIV incidence among 575 people living in the fishing community enrolled in an Observational and SiVET cohorts in South Western Uganda.
Observational cohort | Simulated Vaccine Efficacy Trial | ||||||
---|---|---|---|---|---|---|---|
|
|||||||
Characteristics | Incidence per 100PY | uHR | aHR | Incidence per 100PY | uHR | aHR | |
Overall | 11.4 | 3.8 | |||||
Sex | |||||||
Male | 7.9 | 1 | 1 | 3.1 | 1 | 1 | |
Female | 14.9 | 1.7 (0.7-4.4) | 1.9 (0.9-4.0) | 5.7 | 1.8 (0.5-6.4) | 1.4 (0.4-5.5) | |
Age (years) | |||||||
18-24 | 9.5 | 1 | 1 | 3.6 | 1 | 1 | |
25-34 | 10.5 | 0.9 (0.3-2.8) | 1.5 (0.6-3.7) | 3.4 | 0.9 (0.2-4.1) | 1.3 (0.3-5.9) | |
35-48 | 19.0 | 2.0 (0.6-6.2) | 2.5 (0.9-6.5) | 4.9 | 1.3 (0.3-6.7) | 1.9 (0.4-9.9) | |
Tribe* | |||||||
Baganda | 13.6 | 1 | 0.8 | 1 | 1 | ||
Other | 10.1 | 0.7 (0.3-1.7) | 6.3 | 7.5 (1.0-58.8) | 6.6 (0.8 -52.8) | ||
Education¥ | |||||||
≥Primary school | 9.4 | 1 | 1 | 3.8 | 1 | ||
None | 33.1 | 3.9 (1.4-10.5) | 3.1 (1.3-7.7)* | 5.3 | 1.5 (0.2-11.7) | ||
Religion | |||||||
Christian | 11.2 | 1 | 2.4 | 1 | |||
Muslim | 11.9 | 0.9 (0.3-2.5) | 8.5 | 3.4 (0.9-11.9) | |||
Marital status | |||||||
Single | 6.1 | 1 | 5.0 | 1 | |||
Married | 9.9 | 1.4 (0.4-5.5) | 1.5 | 0.3 (0.1-1.6) | |||
Separated | 19.5 | 3.2 (0.9-11.6) | 7.8 | 1.5 (0.4-5.9) | |||
Occupation | |||||||
Fishing and related business | 10.7 | 1 | 2.6 | 1 | |||
Other | 12.0 | 1.3 (0.5-3.1) | 6.7 | 2.6 (0.7-9.0) | |||
Residence in fishing community (years) ¥ | |||||||
0-1 | 18.4 | 1 | 1 | 9.4 | 1 | 1 | |
>1-5 | 8.2 | 0.5 (0.2-1.2) | 0.5 (0.2-1.2)* | 5.3 | 0.6 (0.2-2.0) | 0.5 (0.1-1.9) | |
>5 | 9.7 | 0.4 (0.1-1.5) | 0.3 (0.1-0.8)* | 0 | - | - | |
Sex while drunk | |||||||
Never | 9.7 | 1 | 3.4 | 1 | |||
Always | 20.6 | 2.2 (0.6-7.6) | 5.0 | 1.4 (0.2-11.2) | |||
Genital discharge | |||||||
Yes | 12.5 | 1 | 3.4 | 1 | |||
No | 10.1 | 0.8 (0.3-2.3) | 3.5 | 1.0 (0.1-8.4) | |||
Genital sores | |||||||
Yes | 14.4 | 1 | 7.0 | 1 | |||
No | 9.4 | 0.7 (0.2-1.8) | 2.8 | 0.4 (0.1-1.8) | |||
Number of partners | |||||||
0-1 | 10.9 | 1 | 3.6 | 1 | |||
2+ | 10.3 | 0.9 (0.3-2.7) | 3.3 | 0.9 (0.2-3.8) | |||
New partner | |||||||
No | 10.8 | 1 | 3.8 | 1 | |||
Yes | 12.7 | 1.2 (0.4-3.2) | 2.8 | 0.8 (0.2-4.0) | |||
Condom use with new partner | |||||||
Never | 13.6 | 1 | 3.2 | 1 | |||
Always | 11.9 | 0.8 (0.2-3.9) | 4.3 | 1.4 (0.1-15.0) |
uHR unadjusted Hazard ratio, p-likelihood p-value, aHR-adjusted Hazard ratio,
unadjusted p<0.05
Both unadjusted and adjusted p <0.05