Table 1.
Int | β0 GR/ mGR |
CML | Int | βX GR/ mGR |
CML | Int | βZ GR/ mGR |
CML | Int | βXZ GR/ mGR |
CML | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
simple random; N = 1000 | ||||||||||||
Bias | −8.94 | −0.79 | −1.12 | 2.42 | 2.16 | 2.46 | 1.29 | 1.29 | 1.65 | 1.39 | 1.30 | 1.87 |
SE | 91.4 | 24.4 | 24.4 | 96.8 | 20.1 | 19.9 | 94.3 | 20.2 | 19.8 | 89.4 | 89.6 | 89.3 |
ESE | 91.8 | 22.9 | 23.5 | 92.3 | 19.8 | 19.7 | 92.4 | 19.9 | 19.8 | 85.8 | 85.3 | 86.9 |
MSE | 8.42 | 0.59 | 0.59 | 9.38 | 0.41 | 0.40 | 8.89 | 0.41 | 0.39 | 7.98 | 8.02 | 7.97 |
CP | 95.4 | 88.6 | 90.8 | 94.3 | 94.6 | 95.2 | 94.6 | 94.4 | 95.5 | 93.6 | 93.4 | 93.8 |
case-control; N = 1000 | ||||||||||||
Bias | - | - | 1.70 | 2.40 | 28.4 | 2.23 | 5.06 | 27.6 | 1.73 | −1.51 | −1.20 | −2.30 |
SE | - | - | 17.4 | 75.7 | 11.3 | 16.7 | 72.2 | 11.4 | 16.6 | 72.9 | 72.8 | 71.7 |
ESE | - | - | 16.6 | 73.3 | 11.6 | 16.5 | 73.1 | 11.6 | 16.5 | 71.4 | 71.3 | 70.1 |
MSE | - | - | 0.30 | 5.73 | 0.93 | 0.28 | 5.24 | 0.89 | 0.28 | 5.31 | 5.29 | 5.15 |
CP | - | - | 90.7 | 94.2 | 31.4 | 94.5 | 95.4 | 33.1 | 94.8 | 94.7 | 94.6 | 93.7 |
Int: internal-data only method
GR: generalized regression, mGR: modified GR for case-control sampling
CML: constrained maximum likelihood
ESE: estimated standard error
MSE: mean squared error
CP: coverage probability of a 95% confidence interval interval