Figure 1.

Gal-3 expression is up-regulated in renal cell carcinoma. Gal-3 was mainly expressed in epithelial cells of the collecting ducts (a) and distal tubules (b), but not in epithelial cells of proximal tubules (c). The black arrows indicate the expression of Gal-3; Red arrows indicate the low expression of Gal-3 in proximal tubules. (d) Gal-3 was highly expressed in RCC; (e) mRNA expression of Gal-3 in various renal tumor cells; (f) Representative blots of Gal-3 expression in renal tumor cells. (A color version of this figure is available in the online journal.)