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. 2016 Aug 22;213(9):1851–1864. doi: 10.1084/jem.20150514

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© 2016 Sun et al.

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Figure 2. — Antibiotic treatment controls lung bacterial burdens. (A–E) WT mice were infected with PR8 and 7 d later superchallenged with MRSA. At 1 dpi, lungs were analyzed for bacterial burdens (A), viral titers (B), protein (C), LDH (D), and albumin levels (E) in BALF. All PR8-infected (Flu), MRSA-infected (MRSA), and coinfected (Flu + MRSA) mice were treated with linezolid or PBS control. #, four out of five coinfected mice died within 24 h in the absence of linezolid treatment; AU, arbitrary units; n.s., not significant. *, P < 0.05; **, P < 0.01, Mann Whitney test. Data shown are representative of two independent experiments.