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. 2016 Aug 22;213(9):1851–1864. doi: 10.1084/jem.20150514

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© 2016 Sun et al.

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Figure 3. — Nox2 activity enhances lung bacterial clearance. (A and B) WT and Nox2-deficient (KO) mice were infected with PR8 and 7 d later superchallenged with MRSA. Lungs were analyzed for bacterial burdens (A) and viral titers (B). All PR8-infected (Flu), MRSA-infected (MRSA), or coinfected (Flu + MRSA) mice were treated daily with linezolid until 24 h before harvesting the samples. *, P < 0.05; **, P < 0.01; ***, P < 0.001, Tukey's multiple comparisons test. n.s., not significant. Data shown are representative of two independent experiments.