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. 2016 Aug 22;213(9):1901–1919. doi: 10.1084/jem.20160204

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© 2016 Liu et al.

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Figure 2. — miR-22 and miR-183/96/182 are dispensable for Tfh cell generation and function. (A, B, D, and E) WT, miR-22^−/−, and miR-183/96/182^−/− mice were immunized with OVA/alum/LPS, and CXCR5^hiBcl6⁺ Tfh cells (A and D) and FAS^hiGL7^hi GC B cells (B and E) were analyzed on day 7 after immunization by flow cytometry. (Left) Representative FACS plots. (Right) Summary of percentages of Tfh and GC B cells. (C and F) In independent experiments, NP-OVA/alum–immunized mice were bled at the indicated time points, and the amounts of NP-specific IgG1 were determined by ELISA. Each symbol represents an individual mouse. Horizontal lines indicate the mean. n = 3–7.