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Water pool above the DNC in the crystal structure of ba3-type CcO from Thermus thermophilus (PDB ID 3S8F). Left: Location of the water pool within the enzyme with surrounding residues highlighted. Purple spheres are metals in the protein (CuA, CuB, Fea3). Subunits I, II and III are shown in yellow, green and purple. Right: Details of the water pool and surrounding residues. The orange region is the water pool consisting of eight crystal waters.
