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. Author manuscript; available in PMC: 2017 Aug 23.
Published in final edited form as: Biochemistry. 2016 Aug 11;55(33):4731–4736. doi: 10.1021/acs.biochem.6b00658

Figure 2.

Figure 2

Pyruvate kinase activity of PKM2G415R. (A) With titration of PEP, the PKM2G415R variant shows a KM of 1.2 mM PEP and kcat 0.57 sec−1. (B) With titration of ADP, PKM2G415R shows a KM of 0.25 mM ADP.