Table 2. Group differences in neural responses to reward and aversion.
Brain region | x | y | z | Z-score | P |
---|---|---|---|---|---|
Anticipatory | |||||
Chocolate cue: FH > controls | |||||
Caudate | 4 | −6 | 6 | 3.43 | 0.004 |
Unpleasant cue: FH > controls | |||||
Planum polare/amygdala | 40 | −6 | −20 | 3.44 | <0.001 |
Caudate | 4 | −6 | 6 | 3.36 | <0.001 |
Thalamus | −2 | −10 | 10 | 3.37 | 0.005 |
Consummatory | |||||
Unpleasant taste: controls > FH | |||||
Superior frontal gyrus | 16 | 32 | 62 | 3.11 | 0.02 |
Pallidum/putamen | 20 | −2 | 6 | 2.86 | 0.02 |
dACC | 10 | 4 | 28 | 2.96 | 0.02a |
P>0.05 with SHAPS as a covariate.
Coordinates are defined in the Montreal Neurological Institute (MNI) stereotactic space. P values whole brain fully corrected at the cluster level (FWE P<0.05 family wise error for multiple comparisons).