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. 2016 Aug 24;7:299. doi: 10.3389/fimmu.2016.00299

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Copyright © 2016 Pradier, Simonetta, Waldvogel, Bosshard, Tiercy and Roosnek.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Impact of licensing on TNF-α production and cytoxicity in CD56^dimCD94^neg cells. TNF-α^pos (A) and CD107^pos (B) cells in CD56^dimCD94^neg cells expressing a single licensed (L) or unlicensed (U) KIR after culture for 3 h in presence of K562 target cells. Medians are shown, and Mann–Whitney test was used for statistical analysis, p values are indicated when significant.