Fig. 4.

NgR1 mRNA expression changes in primary culture astrocytes and microglia received stimulation by lipopolysaccharide (LPS) and cytokine (Transforming growth factor-β=TGF-β, Epidermal Growth Factor=EGF).

a), b) Astrocytes were stimulated with TGF-β and EGF. NgR1 mRNA expression by Q-PCR was significantly elevated in activated astrocytes stimulated with TGF-β.

c) NgR1 mRNA in activated microglia stimulated with LPS was expressed at a significantly lower level compared to that without stimulation.