Table 1. Numerical data for individual mice used in osteoblast study, lettering corresponding to graphs in Fig. 7 and Supplementary Data S1.
| Mouse | NDUFB8 osteoblasts |
COX-I osteoblasts |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Pos | Int (+) | Int (−) | Neg | z-score | Pos | Int (+) | Int (−) | Neg | z-score | ||
| 4 month wild type mice | A | 100.0% | 0.0% | 0.0% | 0.0% | −0.2645 | 100.0% | 0.0% | 0.0% | 0.0% | 0.1219 |
| B | 100.0% | 0.0% | 0.0% | 0.0% | 0.4862 | 98.0% | 2.0% | 0.0% | 0.0% | −0.2462 | |
| C | 100.0% | 0.0% | 0.0% | 0.0% | −0.0199 | 100.0% | 0.0% | 0.0% | 0.0% | 0.0991 | |
| D | 99.2% | 0.8% | 0.0% | 0.0% | −0.1050 | 100.0% | 0.0% | 0.0% | 0.0% | −0.0740 | |
| E | 100.0% | 0.0% | 0.0% | 0.0% | −0.1375 | 100.0% | 0.0% | 0.0% | 0.0% | −0.0057 | |
| 11 month wild type mice | F | 61.5% | 25.0% | 8.7% | 4.8% | −2.5793 | 85.6% | 8.7% | 2.9% | 2.9% | −1.7644 |
| G | 65.1% | 25.6% | 8.1% | 1.2% | −2.3037 | 46.5% | 21.0% | 19.8% | 12.8% | −3.1797 | |
| H | 90.1% | 8.9% | 1.0% | 0.0% | −1.0015 | 87.1% | 7.9% | 3.0% | 2.0% | −1.0838 | |
| I | 69.3% | 24.8% | 3.9% | 2.0% | −2.3267 | 82.2% | 13.9% | 1.0% | 3.0% | −1.6834 | |
| J | 69.0% | 17.7% | 10.6% | 2.7% | −2.2288 | 74.3% | 17.7% | 7.1% | 0.9% | −1.5172 | |
| K | 94.3% | 5.7% | 0.0% | 0.0% | −0.7150 | 72.7% | 14.8% | 9.1% | 3.4% | −1.4310 | |
| L | 77.9% | 9.5% | 4.2% | 8.4% | −1.6644 | 67.4% | 21.1% | 9.5% | 2.1% | −2.0048 | |
| M | 44.4% | 50.0% | 5.6% | 0.0% | −3.1335 | 75.0% | 19.4% | 4.6% | 0.9% | −1.7746 | |
| 11 month PolgA mice | N | 1.9% | 3.9% | 8.7% | 85.5% | −9.0776 | 12.6% | 8.7% | 5.8% | 72.8% | −10.9406 |
| O | 3.4% | 10.3% | 8.0% | 78.2% | −8.9053 | 3.4% | 3.4% | 2.3% | 91.0% | −15.9127 | |
| P | 0.0% | 0.9% | 4.6% | 94.4% | −9.1844 | 3.7% | 4.6% | 2.8% | 88.9% | −14.9438 | |
| Q | 2.8% | 0.9% | 5.6% | 90.7% | −9.7061 | 6.5% | 4.6% | 2.8% | 86.1% | −14.1500 | |
| R | 3.0% | 12.1% | 24.2% | 60.6% | −6.6788 | 12.1% | 5.1% | 9.1% | 73.7% | −10.0046 | |
| S | 6.7% | 10.6% | 18.3% | 64.4% | −6.6901 | 3.8% | 5.8% | 1.9% | 88.5% | −13.3303 | |
| T | 0.9% | 1.7% | 1.0% | 90.3% | −8.1441 | 9.6% | 0.9% | 3.5% | 86.0% | −12.7954 | |
| U | 5.1% | 14.7% | 38.2% | 42.0% | −5.7412 | 5.1% | 5.1% | 3.7% | 86.0% | −12.1565 | |
| V | 4.1% | 0.8% | 4.9% | 90.2% | −9.9374 | 4.9% | 0.8% | 3.3% | 91.1% | −17.1963 | |
Percentages of osteoblasts for individual mice which are positive, intermediate positive, intermediate negative and negative for NDUFB8 and COX-I protein expression are shown. Osteoblasts were classed as having normal levels (positive) if Z-scores were no more than −3SD from the mean, intermediate (+) if Z-scores were between −3SD and −4.5SD, intermediate (−) if Z-scores were between −4.5SD and −6SD, and deficient if Z-scores were more than −6SD below the mean. Average Z-scores for NDUFB8:porin and COX-I:porin are also shown.