Figure 6. Putative membrane topology model showing residues involved in the ability of OsMTP8.1 to confer tolerance to Mn in yeast.

The membrane topology model of OsMTP8.1 is based on alignment with EcYiiP. Residues whose mutation resulted in loss of Mn tolerance conferred to yeast are shown in red. Residues whose mutation significantly decreased Mn tolerance conferred to yeast are shown in blue. Residues whose mutation slightly decreased Mn tolerance conferred to yeast are shown in green. Residues whose mutation increased the Zn tolerance conferred to yeast are shown in yellow.