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. 2016 Aug 24;6:31725. doi: 10.1038/srep31725

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Best performing form among six variations (Eqns 7 and 8) from CAS, PAS, EXPR, PHYL, funsim as well as PROFILE were compared in terms of ranks of correct enzymes at each EEN position. N1 and N2 in the figure legend stand for k = 1 and 2 for Rel_Score. (A) Feature scores computed using the original GO annotations. MRR for CAS, PAS, EXPR, PHYL, funsim, and PROFILE were 0.294, 0.077, 0.055, 0.096, 0.191, and 0.617, respectively. (B) Scores computed using parental GO terms mapped at the 4^th level. MRR for CAS, PAS, EXPR, PHYL, funsim, and PROFILE were 0.156, 0.024, 0.055, 0.096, 0.134, and 0.314, respectively.