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. 2016 Aug 24;6:32091. doi: 10.1038/srep32091

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) Putative miR-153 binding sites predicted by targetscan in 3′-UTR of human HIF-1α gene. (b,c) Transfection of miR-153 mimics significantly reduces expression of HIF-1α in astrocytes as compared with control transfection with vehicle or miR-328 mimics. (d,e) Transfection of miR-153 inhibitor significantly enhanced expression of HIF-1α in astrocytes as compared with transfection with vehicle or miR-328 inhibitor.