Table 3. Univariate and multivariate linear regression analysis for the associations among plasma sST2 and HR-pQCT parameters.
| Unadjusted |
Adj. for age, gender |
Adj. for age, gender, BMI, HT, DM, ESR, CRP |
||||
|---|---|---|---|---|---|---|
| Coefficients (95%CI) | P value | Coefficients (95%CI) | P value | Coefficients (95%CI) | P value | |
| vBMD, mgHA/cm3 | ||||||
| Average vBMD | −0.129 (−4.236, −3.978) | 0.950 | ||||
| Ct. vBMD | −5.406 (−8.550, −2.263) | 0.001 | −4.603 (−7.835, −1.372) | 0.006 | −2.918 (−6.111, 0.275) | 0.073 |
| Tb. vBMD | 2.107 (−0.151, 4.366) | 0.067 | 0.895 (−1.425, 3.214) | 0.445 | ||
| pTb. vBMD | 2.535 (0.355, 4.715) | 0.023 | 1.518 (−0.751, 3.786) | 0.187 | ||
| mTb.vBMD | 1.833 (−0.541, 4.206) | 0.128 | ||||
| Trabecular microstructure | ||||||
| BV/TV | 0.002 (0.000, 0.004) | 0.068 | 0.001 (−0.001, 0.003) | 0.450 | ||
| Tb. number, mm−1 | 0.026 (0.011, 0.042) | 0.001 | 0.023 (0.006, 0.040) | 0.009 | 0.024 (0.006, 0.041) | 0.008 |
| Tb. thickness, mm | 0.000 (−0.001, 0.001) | 0.897 | ||||
| Tb. separation, mm | −0.010 (−0.019, −0.001) | 0.034 | −0.006 (−0.017, 0.004) | 0.208 | ||
| Inhomogeneity, mm | −0.004 (−0.011, 0.003) | 0.238 | ||||
| Cortical microstructure | ||||||
| Ct. TMD, mgHA/cm3 | −2.538 (−4.540, −0.536) | 0.014 | −1.791 (−3.894, 0.311) | 0.094 | −0.723 (−2.808, 1.363) | 0.492 |
| Ct. thickness, mm | 0.009 (−0.007, 0.024) | 0.257 | ||||
| Ct. PoV, mm3 | 2.973 (1.371, 4.575) | <0.001 | 2.917 (1.142, 4.693) | 0.002 | 2.247 (0.434, 4.060) | 0.016 |
| Ct. Po, % | 0.248 (0.116, 0.380) | <0.001 | 0.246 (0.105, 0.386) | 0.001 | 0.184 (0.042, 0.325) | 0.012 |
| Ct. Po. Dm, mm | −0.001 (−0.002, 0.001) | 0.410 | ||||
vBMD: volumetric bone mineral density, Ct.: cortical, Tb.: trabecular, TMD: tissue mineral density, Po: porosity index, PoV: pore volume, Po. Dm: pore diameter, BMI: body-mass index, HT: hypertension, DM: diabetes, ESR: erythrocyte sedimentation rate, CRP: c-reactive protein.