Table 2. Effect of standard v. enhanced disclosure on depressed patients’ willingness to enter a placebo-controlled antidepressant clinical trial v. individual psychiatric treatment.
| Standard disclosure (n = 126) |
Enhanced disclosure (n = 147)a |
χ2 | d.f. | P | |
|---|---|---|---|---|---|
| Willingness scale score, mean (s.d.) | 3.9 (1.8) | 4.5 (1.5) | 0.002b | ||
| % Willing to enroll in RCT, n (%) | 52 (41.3) | 35 (23.8) | 9.53 | 1 | 0.002c |
a
There were 3 missing responses in the standard arm and 2 in the enhanced arm.
b
Two-sided Mann-Whitney test. Willingness measured on a 1–6 scale where 1 = “I would definitely choose the research study” and 6 = “I would definitely choose treatment with a psychiatrist”.
c
Two-sided chi-square test. The participants were divided into two groups. Those answering 1–3 on the willingness scale were grouped as preferring the RCT and those answering 4–6 were grouped as preferring individual treatment.