Table 2. Clinical data of patients with IgA nephropathy (non-crescentic IgA-GN (IgA-GN) and cellular-crescentic IgA-GN (crescentic IgA-GN)) and controls. If no unit is given data are presented as total count, otherwise as median (25th/75th percentile).
| IgA-GN; n = 5 | Crescentic-IgA-GN; n = 5 | Controls; n = 5 | |
|---|---|---|---|
| Female | 2 | 3 | 4 |
| Age at biopsy | 47.0 (37.0/51.0) | 46.0 (17.0/65.0) | 37.0 (24.0/55.0) |
| Crescents per total glomeruli count (%) | 0 (0/0) | 44.4 (36.6/46.2) | 0 (0/0) |
| Global glomerulosclerosis per total glomeruli count (%) | 5.9 (5.9/6.3) | 9.8 (0/10) | 0 (0/0) |
| Arterial hypertension WHO-Grade | |||
| 0 | 3 | 2 | 3 |
| 1 | 1 | 2 | 1 |
| 2 | 1 | 0 | 0 |
| 3 | 0 | 1 | 0 |
| n.d. | 0 | 0 | 1 |
| Proteinuria | |||
| normal | 0 | 0 | 2 |
| <3.5 g/day | 5 | 3 | 3 |
| >3.5 g/day | 0 | 2 | 0 |
| n.d. | 0 | 0 | 0 |
| Microhematuria | 5 | 4 | 2 |
| Macrohematuria | 1 | 1 | 0 |
| Haemoglobin (g/dl) | 13.1 (11.1/15.4) | 10.9 (10.8/12.7) | 12.5 (9.1/14.1) |
| Leukocytes (103/μl) | 6.8 (5.6/7.4) | 8.1 (7.7/8.8) | 8.8 (5.7/11.3) |
| Thrombocytes (103/μl) | 237 (192/257) | 360 (292/401) | 245 (166/484) |
| Serum-Creatinine (μmol/l) | 84 (68/232) | 107 (79/450) | 273 (129/465) |
| eGFR MDRD (ml/min) (Schwartz if age <18 years) | 88.8 (42.2/96.0) | 54.7 (22.1/95.5) | 18.0 (15.8/40.8) |
Although serum creatinine of controls was higher than those in patients with IgA nephropathy, there were no significant differences. Furthermore, there were no significant differences for eGFR (Steel-Dwass test).