Fig. 4.

Ophiocordyceps formosana improved depressive-like behaviors in STZ-induced diabetic mice. a Locomotor activity in the open filed test (OFT) (b) The ratio of retention time in the central zone to total duration time in the OFT. c The ratio of the retention time in the open arm to total duration of the equipment (%) in the elevated plus maze (EPM). d The immobility time in the tail suspension test (TST). * represent p ≤ 0.05, Control-PBS vs. STZ-PBS. One way ANOVA followed by Tukey’s post hoc test was performed for multiple comparisons. Mean in a row with different superscripts is significantly different (p ≤ 0.05). Values are mean ± SEM, n = 6 in control group and n = 8 in all STZ-treated groups