Table 2.
BRCA1/2 mutation frequencies in patients with TNBC and non-TNBC
TNBC (N = 192) | Non-TNBC (N = 331) | P a | |
---|---|---|---|
Mutation status | n (%) | n (%) | |
Carriers | 73 (38.0) | 52 (15.7) | < 0.0001 b |
BRCA1 | 71 (37.0) | 34 (10.3) | < 0.0001 c |
BRCA2 | 2 (1.0) | 18 (5.4) | NSd |
Non-carriers | 119 (62.0) | 279 (84.3) |
P values marked in bold are statistically significant
NS non-significant, TNBC triple-negative breast cancer
aFisher’s exact test. bCarriers vs. non-carriers. c BRCA1 carriers vs. non-carriers
d BRCA2 carriers vs. non-carriers