Table 5.

Ratio of the probability of carrying BRCA1/2 mutations in the investigated patients collective relying on multiple logistic regression model

		Non-carriers		BRCA1 mutation carriers
Variables	Level	n	%	n	%	RP	95%CI	P
Family phenotype	1 early onset BC (≤ 30 years)	210	53	21	20	Ref.		< 0.0001
	Familial BC	166	42	56	53	4.98	2.77 to 8.97
	Familial BC and OC	22	6	28	27	16.22	7.22 to 36.5
Histology	Ductal	359	90	102	97	Ref.		0.36
	Other	39	10	3	3	0.53	0.13 to 2.08
Tumor grade	1	5	1	0	0	-		0.001
	2	116	29	6	6	0.17	0.07 to 0.43
	3	253	64	94	90	Ref.
	Unknown	24	6	5	5	0.39	0.12 to 1.20
TNBC status	Non-TNBC	279	70	34	32	Ref.		< 0.0001
	TNBC	119	30	71	68	4.23	2.50 to 7.14

P values marked in bold are statistically significant

BC breast cancer, OC ovarian cancer, Ref. reference, RP ratio of the probability of carrying BRCA1/2 mutations