Table 4.
Logistic regression estimates for the association between microvessel density (MVD) and breast biopsy diagnosis
| Breast biopsy diagnosis | N | OR (95 % CI)a | P |
|---|---|---|---|
| Non-case | 174 | 1.00 | 0.005 |
| Case | 44 | 1.69 (1.17–2.44) | |
| Non-case | 174 | 1.00 | 0.002 |
| In situ carcinoma | 36 | 1.36 (0.91–2.04) | |
| Invasive | 8 | 4.86 (1.91–12.38) | |
| Benign | 50 | 1.00 | 0.002 |
| Proliferative | 99 | 1.56 (1.04–2.33) | |
| Proliferative with atypia | 25 | 1.47 (0.84–2.58) | |
| In situ carcinoma | 36 | 1.89 (1.13–3.15) | |
| Invasive | 8 | 6.81 (2.52–18.42) | |
| Ordinal odds ratio | 1.66 (1.27–2.16) | 0.002 |
The average of MVD within a woman was computed and standardized by one standard deviation. Non-cases: non-proliferative benign breast disease, proliferative (ductal hyperplasia; sclerosing adenosis), proliferative with atypia (atypical ductal or lobular hyperplasia). Cases: ductal or lobular carcinoma in situ and invasive cancer
aAdjusted for age at biopsy (39–44, 45–49, 50–54, 55–59, 60–65 years) and BMI (<25, 25– < 30, 30+ kg/m2)