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. 2016 Aug 22;240(1):3–14. doi: 10.1002/path.4745

Figure 4.

PATH-4745-FIG-0004-b

TAZ S89A activates genes associated with human cancer. (A) Effects of TAZ, mutant TAZ S89A and YAP S127A expression on Hippo pathway reporter constructs 8XGTIIC–Luc, CTGF–Luc and Brachyury–Luc in C2C12 myoblasts. (B) Validation of the expression of human WWTR1 and effects of TAZ or TAZ S89A expression in C2C12 myoblasts on expression of Ctgf, Myf5, Phgdh, Psat1 and Psph. Data are expressed as mean ± SD, where n = 3 and * indicates a significant difference (p < 0.05) when compared to control using one‐way ANOVA