Table 1.
Clinical characteristics of the study patients
| Characteristic | Case 1 patient | Case 2 patient | Case 3 patient |
|---|---|---|---|
| Age (years) | 7 | 7 | 9 |
| Gender | M | M | M |
| Clinical diagnosis | DHF grade III | DHF grade III | DHF grade III |
| RT-PCR | DENV-2 | DENV-2 | DENV-2 |
| Serologic response | Secondary | Secondary | Secondary |
| Fever day at admission | 0 | –1 | 0 |
| Percent hemoconcentration | 28 | 44 | 39 |
| Pleural effusion index | 41 | 66 | 26 |
| Clinical evidence of shock | |||
| Systolic BP <80 mmHg | N | Y | N |
| Pulse pressure <20 mmHg | Y | Y | Y |
| Cold extremities | Y | Y | Y |
| Minimum systolic BP (mmHg) | |||
| Study day 1 | 97 | 74 | 97 |
| Study day 2 | 96 | 87 | 93 |
| Minimum pulse pressure (mmHg) | |||
| Study day 1 | 26 | 15 | 29 |
| Study day 2 | 18 | 15 | 15 |
| Fluid intake (ml/kg) | |||
| Study day 1 | 46 | 63 | 25 |
| Study day 2 | 53 | 100 | 86 |
| Study day 3 | 30 | 20 | 46 |
| Study day 4 | 21 | 20 | 35 |
| Transfusion (ml/kg) | 4.9 (study day 1) | None | None |
| Other findings | Ascites, upper GI bleeding | Ascites | Ascites, hemoconcentration, petechiae |
| Length of hospital stay, days | 6 | 5 | 5 |
BP blood pressure, DENV dengue virus, DHF dengue hemorrhagic fever, GI gastrointestinal, M male, N no, RT-PCR reverse transcriptase polymerase chain reaction, Y yes