Table 4.
Expression of genes in WT and lmx1bb mutant embryos
| Marker | 48 h | WT | lmx1bb -/- |
|---|---|---|---|
| GAD | Mean | 114.2 | 109.5 |
| SEM | 1.2 | 4.5 | |
| n | 5 | 4 | |
| p value | 0.54 | ||
| slc6a5 | Mean | 208.3 | 201.2 |
| SEM | 4.9 | 6.2 | |
| n | 6 | 6 | |
| p value | 0.38 | ||
| pax2a | Mean | 138 | 140 |
| SEM | 3.4 | 3.4 | |
| n | 7 | 5 | |
| p value | 0.7 | ||
| lbx1a | Mean | 96.5 | 96.1 |
| SEM | 3.6 | 2.4 | |
| n | 8 | 8 | |
| p value | 0.93 | ||
| evx | Mean | 90.9 | 92.1 |
| SEM | 1.9 | 3.9 | |
| n | 10 | 6 | |
| p value | 0.78 | ||
| Tg(evx1:EGFP) SU1 | Mean | 94.9 | 96.3 |
| SEM | 2.6 | 0.94 | |
| n | 8 | 8 | |
| p value | 0.63 | ||
Mean number of gad1b + gad2 (GAD), slc6a5, pax2a, lbx1a, evx1 + evx2 (evx) or Tg(evx1:EGFP) SU1 -expressing cells in the spinal cord region adjacent to somites 6–10 in 48 h embryos. SEM is the standard error of the mean. n is the number of embryos analyzed for each data set. p value is from a student’s paired t-test comparing WT and lmx1bb mutant embryos