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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Ann Surg Oncol. 2016 May 19;23(9):2816–2824. doi: 10.1245/s10434-016-5249-5

TABLE 3.

Competing risk multivariable model for invasive versus in situ recurrence

Invasive recurrence
In situ recurrence
HR p value HR p value
Age
 <40 1 1
 40 – 49 0.48 0.01 1.33 0.4
 50 – 59 0.33 0.0002 0.69 0.3
 60 – 69 0.29 0.00008 0.88 0.7
 70 – 79 0.36 0.003 0.81 0.6
 ≥80 0.14 0.01 0.24 0.06

Presentation 0.8 0.02
 Clinical 1.07 1.61
 Radiological 1 1

Family History 0.3 0.04
 No 1 1
 Yes 1.21 1.38

Necrosis 0.2 0.02
 Absent 1 1
 Present 1.27 1.5

Number of excisions 0.8 0.007
 ≤2 1 1
 ≥3 1.1 1.92

Margin status 0.2 0.1
 Close/positive 1.31 1.33
 Negative 1 1

Radiation therapy 0.00004 <0.00001
 Yes 0.43 0.45
 No 1 1

Endocrine therapy 0.02 0.003
 Yes 0.53 0.49
 No 1 1

Year of surgery 0.9 0.0005
 ≤1998 1 1
 ≥1999 1.03 0.56