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Quantitative analysis of micro-CT imaging. Images were analyzed for reactive new bone (callus) formation and cortical bone destruction in mice infected with LAC, UAMS-1 (U1), or their isogenic sarA mutants (ΔsarA). Sham, results of the same analysis with mice subjected to the surgical procedure and injected with sterile PBS. *, statistical significance compared to the results of sham treatment; **, statistical significance compared to the results for the isogenic parent strain.
