Fig. 9.

Inflammatory cytokines and chemokines in airways of allergen-challenged WT and Gal-1–deficient mice. (A) Eotaxin-1 and -2 (Eot-1, Eot-2) levels in the BALF of saline- and OVA-challenged WT and Lgals1^−/− mice. (B) IL-5, TNF-α, and IL-13 levels in lung lysates from the above groups of mice. Combined data (mean ± SEM) of mice from three independent experiments (n = 7–9 mice for OVA groups and n = 6–7 mice for saline groups) are shown in A and B. (C) Recruitment of i.v. infused CFSE-labeled BM eosinophils from WT or Lgals1^−/− mice to the peritoneum of mice with TG-induced inflammation. Combined data (mean ± SD) of two out of three experiments in duplicate mice with similar results are shown.