Table 2.
Identified proteins in control or mutant DISC1 primary astrocytes
| Function | Protein | Ratio mutant/control | p value |
|---|---|---|---|
| Metabolism | Glycerol-3-phosphate dehydrogenase, mitochondrial (GPDM) | 1.52 | 0.0396 |
| Transcription/translation | Heat shock cognate 71 kDa protein (HSP7C) | 1.53 | 0.0406 |
| Development | Neuronal membrane glycoprotein M6-a (GPM6A) | 3.66 | 0.0033 |
| Cell-cell interaction | Extracellular matrix protein 2 (ECM2) | 0.28 | 0.0090 |
| Cytoskeleton | Tubulin beta-2B chain (TBB2B) | 1.71 | 0.0341 |
| Tubulin beta-5 chain (TBB5) | 1.27 | 0.0360 | |
| Cytoskeleton-associated protein 4 (CKAP4) | 1.44 | 0.0373 | |
| Actin, cytoplasmic 2 (ACTG) | 0.64 | 0.0434 | |
| Unknown | Transmembrane protein 43 (TMM43) | 1.80 | 0.0152 |
| Epoxide hydrolase 1 (HYEP) | 1.38 | 0.0179 | |
The table includes UniProt IDs, ratios (calculated based on the average) and p values. The adjusted p values for the astrocytes were 0.9834. Significant proteins with an increase/decrease greater than 10% are depicted here.