Fig. 4.
Psychiatric symptoms, SNAP-25 mRNA and protein level in BP, schizophrenia and normal controls. a Psychiatric symptom level at the end of life: Barratt (Barratt Impulsiveness Scale), BPRS (Brief Psychiatric Rating Scale), total BISS (total BISS score), depression (BISS depression factor score), mania (BISS factor score), irritability (BISS irritability factor score), anxiety (BISS anxiety factor score) and psychosis (BISS psychosis factor score). 1 = Significant (p < 0.05) difference between normal control and BP, and between normal control and schizophrenia groups; 2 = significant difference (p < 0.05) between normal control and schizophrenia, and nonsignificant (p = 0.07) difference between normal control and BP; 3 = significant difference between normal control and BP, and nonsignificant difference (p = 0.06) between normal control and schizophrenia groups. Error bars = ±1 SD. b SNAP-25 mRNA levels. c SNAP-25 protein levels. d SNAP-25b/a BA24 protein and mRNA levels; SNAP-25b/a BA24 ratio, and pan (total) SNAP-25 mRNA BA9/BA24 ratio.
