Table 3.
Demographic and symptom data by history of family psychiatric illness
| Without family psychiatric history |
With family psychiatric history |
p | |||
|---|---|---|---|---|---|
| n | mean ± SD | n | mean ± SD | ||
| Handedness (left/right) | 3/16 | 1/6 | 0.9 | ||
| Ethnicity (Hispanic/Anglo-American) | 2/17 | 3/4 | 0.3 | ||
| Sex (male/female) | 12/4 | 4/2 | 0.7 | ||
| Smoking (yes/no) | 12/4 | 5/1 | 0.7 | ||
| Suicide (yes/no) | 2/14 | 2/4 | 0.3 | ||
| AUD (yes/no) | 1/15 | 3/3 | 0.04 | ||
| Substance use disorder (yes/no) | 0/16 | 6/6 | <0.7 | ||
| Psychiatric diagnosis (yes/no) | 5/11 | 6/0 | 0.004 | ||
| Antidepressant use (yes/no) | 4/15 | 4/3 | 0.08 | ||
| Benzodiazepine use (yes/no) | 1/18 | 0/7 | 0.5 | ||
| Antiseizure mood stabilizer use (yes/no) | 2/17 | 1/6 | 0.8 | ||
| Neuroleptic use (yes/no) | 2/17 | 4/3 | 0.03 | ||
| Age, years | 16 | 57 ± 11 | 6 | 44 ± 10 | 0.04 |
| Postmortem interval, h | 16 | 27 ± 5 | 6 | 30 ± 4 | 0.5 |
| pH | 16 | 6.3 ± 0.3 | 6 | 6.2 ± 0.3 | 0.1 |
| RNA integrity number | 16 | 7.1 ± 09 | 6 | 7.1 ± 1.1 | 0.9 |
| Total BISS score | 13 | 14.3 ± 22 | 5 | 49 ± 32 | 0.007 |
| BISS mania factor score | 13 | 4 ± 1 | 5 | 12 ± 7 | 0.8 |
| BISS depression factor score | 13 | 4 ± 12 | 5 | 20 ± 9 | 0.01 |
| BISS irritability factor score | 13 | 2 ± 3.5 | 5 | 6.4 ± 7 | 0.1 |
| BISS anxiety factor score | 13 | 2 ± 5 | 5 | 6.6 ± 5 | 0.04 |
| BISS psychosis factor score | 13 | 0.8 ± 2 | 5 | 4.2 ± 4 | 0.04 |
| BPRS | 13 | 23 ± 14 | 5 | 38 ± 17 | 0.04 |
| Barratt Impulsiveness score | 13 | 54 ± 15 | 5 | 86 ± 20 | 0.007 |
BPRS = Brief Psychiatric Rating Scale. Medications are those that were prescribed at the time of death. Bold print indicates p < 0.05.