Table 2. . Pharmacokinetic parameters.

Injected agent	Taxotere		PRINT-docetaxel		PRINT-C2-dimethyl-Si-docetaxel				Conversion of C2-docetaxel to docetaxel
Analyte	Docetaxel		Docetaxel		C2-docetaxel		Docetaxel
	AUC ng/ml*h	Cmax ng/ml	AUC ng/ml*h	Cmax ng/ml	AUC ng/ml*h	Cmax ng/ml	AUC ng/ml*h	Cmax ng/ml
Plasma	4742	10,256	326,352	147,694	360,281	125,535	7683	5475	2.1%
Contralateral brain	189	535	4274	1516	5892	1772	109	90	1.8%
Peri-tumoral brain	118	252	2546	1516	4011	1740	125	89	3.0%
Brain tumor	372	394	4885	8558	2634	1704	321	120	10.9%