Table 3. . Survival rate of mice after tail vein injection of PEI/DNA or LGA-PEI/DNA nanoparticles.
PEI/DNA delivery† (n = 3) (μg DNA) | Survival rate (%) | LGA-PEI/DNA (2.5:1 w/w) delivery (n = 4) (μg DNA) | Survival rate (%) |
---|---|---|---|
30 |
100 |
30 |
100 |
50 |
0 |
50 |
100 |
100 |
- |
100 |
100 |
200 | - | 200 | 50 |
†LGA-PEI (0.5:1 w/w) polymer was used.
LGA-PEI: Lactic-co-glycolic acid-modified polyethylenimine; PEI: Polyethylenimine.