Table 3.

The level of IFN γ in the studied subgroups

	Ia	Ib	Ic	Id	IIa1	IIb1	Ie	IIa2	IIb2
IFN γ
Min.–Max.	21.34–46.88	155.20–362.70	74.55–101.33	214.05–491.18	323.20–1,251.34	229.68–1,068.80	181.96–657.78	362.70–1,450.60	102.42–1,185.65
Mean ± SD	34.39 ± 8.39	254.77 ± 68.78	89.65 ± 9.0	275.0 ± 78.56	501.53 ± 277.06	536.74 ± 279.34	456.52 ± 157.71	588.07 ± 341.86	590.20 ± 351.19
Median	35.14	249.66	90.49	256.97	408.45	454.91	423.67	451.84	596.40
p1		<0.001*	<0.001*	<0.001*	<0.001*	<0.001*	<0.001*	<0.001*	<0.001*
p2		<0.001*			0.940			0.650
p3					0.001*	0.023*		0.496	0.290

Ia normal non infected control subgroup, Ib chitosan delivery control subgroup (BCNS), Ic FIA adjuvant control subgroup (FIA), Id virulent RH infected control subgroup, Ie avirulent Me49 infected control subgroup, IIa1 CTLVECNS vaccinated subgroup challenged with virulent RH strain, IIa2 CTLVECNS vaccinated subgroup challenged with avirulent Me49 strain, IIb1 CTLV + FIA vaccinated subgroup challenged with virulent RH strain, IIb2 CTLV + FIA vaccinated subgroup challenged with avirulent Me49 strain, p1 p value for Mann–Whitney test between subgroup Ia and other subgroups, p2 p value for Mann–Whitney test between subgroup Ib and Ic, subgroup IIa1 and IIb1–subgroup IIa2 and IIb2, p3 p value for Mann–Whitney test between subgroup Id and IIa1, IIb1–subgroup Ie and IIa2, IIb2

* Statistically significant at p ≤ 0.05