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. 2016 Jan 6;5:1–13. doi: 10.2147/OV.S66083

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© 2016 Simpson et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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A summary of immunogenic cell death (ICD) caused by oncolytic virus and/or chemotherapy.

Note: Reproduced from Woller N, Gürlevik E, Ureche C-I, Schumacher A, Kühnel F. Oncolytic viruses as anticancer vaccines. Front Oncol. 2014;4:188. doi: 10.3389/fonc. 2014.00188.¹⁴⁸

Abbreviations: Ads, adenoviruses; APCs, antigen-presenting cells; DAMPs, danger-associated molecular patterns; DCs, dendritic cells; dsRNA, double-stranded RNA; EGFR, epidermal growth factor receptor; ER, endoplasmic reticulum; HSV, herpes simplex virus; IFN, interferon; MV, measles virus; NDV, Newcastle disease virus; PAMPs, pathogen-associated molecular patterns; PRRs, pattern recognition receptors; PV, parvovirus; ROS, reactive oxygen species; ssRNA, single-stranded RNA; TAAs, tumor-associated antigens; TNF, tumor necrosis factor; VV, vaccinia virus.