Table 2. Correlation between MED12 exon 2 mutation status and patient age and tumor size in patients with fibroepithelial tumors.
Age (Mean ± SD) MED12 mutant | n | Age (Mean ± SD) MED12 wild-type | n | P value | |
---|---|---|---|---|---|
Fibroadenoma | 31.8 ± 1.9 | 17 | 37.1 ± 3.7 | 9 | 0.158 |
Benign PT | 42 ± 2.2 | 22 | 36.3 ± 8.1 | 3 | 0.404 |
Borderline PT | 49.3 ± 4.5 | 7 | 44.5 ± 2.5 | 2 | 0.604 |
Tumor size (cm) (Mean ± SD) MED12 mutant | n | Tumor size (cm) (Mean ± SD) MED12 wild-type | n | P value | |
Fibroadenoma | 1.7 ± 0.2 | 17 | 2.2 ± 0.3 | 9 | 0.168 |
Benign PT | 2.3 ± 0.2 | 22 | 2.4 ± 1.3 | 3 | 0.899 |
Borderline PT | 5.8 ± 1.2 | 7 | 5.8 ± 3.1 | 2 | 0.986 |
Student's t-tests, two-tailed. PT, phyllodes tumor; SD, standard deviation. Malignant PTs were excluded from this comparison due to small sample size and the low frequency of MED12 mutations.