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Cultivation in the r-3D-KITChip sensitizes primary human hepatocytes to acetaminophen-induced intoxication. The cells were cultivated in the presence of acetaminophen (100 μM and 1000 μM) for 24 h. Their viability was determined by the conversion of resazurin into resorufin and is depicted as % of untreated cells. The graph was drawn with GraphPad Prism software (GraphPad Software, version 5.01). Values are depicted as mean and standard deviation of three donors/experiments.
