Table 4.
Overlap (%) of significant antigens between single-run and cross-run class comparison analysis (p < 0.001). This calculation was done with the same data set in an unnormalized state, quantile-normalized, DWD-adjusted data, and ComBat-adjusted data. SCLC = small cell lung cancer, SqLC = squamous cell lung cancer, LCLC = large cell lung cancer, AdCa = adenocarcinoma.
| Data pre-processing | class comparison overlap (%) from single-run and cross-run analysis | |||
|---|---|---|---|---|
| SCLC | SqLC | LCLC | AdCa | |
| unnormalized | 17.8 | 10.0 | 38.9 | 7.4 |
| QNORM | 41.6 | 18.3 | 39.2 | 31.7 |
| ComBat | 43.4 | 25.7 | 39.1 | 38.3 |
| DWD | 13.7 | 9.5 | 39.6 | 30.0 |