Table 1.

Detection methods applicable to the development of protein microarray technology.

		Labeling/Preparation	Handling	Instrumentation Cost	Quantitative	High Throughput
Labeling	Fluorescent probe	Yes/Medium	Easy	Inexpensive	Yes/No	Yes
	Radioisotope	Yes/Difficult	Difficult	Medium	Yes	Yes/No
	Chemiluminescent probe	Yes/Medium	Easy	Inexpensive	Yes/No	Yes
	Electrochemical probe	Yes/Medium	Easy	Inexpensive	Yes	Yes/No
	Nanoparticles	Yes/Medium	Easy	Inexpensive	Yes	Yes
Non-Labeling	MS	No/Easy	Easy	Expensive	No	Yes/No
	Microcantilever	No/Difficult	Difficult	Expensive	Yes	No
	QCM	No/Medium	Easy	Inexpensive	Yes	No
	SPR	No/Medium	Easy	Expensive	Yes	Yes
	AR	No/Medium	Easy	Inexpensive	Yes	Yes