Figure 4.

Improvement in the structure of adipose tissues and changes in gene expression in brown/beige fat in diet-induced obesity mice. (A): Hematoxylin and eosin staining of representative adipose sections from mice of the indicated groups (scale bar = 200 µm). (B): Quantitative polymerase chain reaction for brown adipose-specific genes in abdominal adipose tissues from mice of the indicated groups (∗, p < .05; ∗∗, p < .01). Abbreviations: AD-MSC, adipose-derived mesenchymal stem cell; PGC-1α, peroxisome proliferator-activated receptor γ coactivator 1-α; Predm 16, PRD1-BF1-RIZ1 homologous domain-containing 16; UC-MSCs, umbilical cord-derived mesenchymal stem cells; UCP-1, uncoupling protein 1.