Figure 7.

Verification of disease phenotype in iPSC-derived cartilage. Cartilage tissues in teratoma were positively stained with Safranin-O, shown as red (top row; scale bar, 500 µm). Aggrecan stained brown in teratoma cartilage from each iPSC line (middle row; scale bar, 500 µm). Corresponding magnified images of aggrecan staining in teratoma cartilage (bottom row; scale bar, 100 µm). Abbreviations: FOCD-NS, familial osteochondritis dissecans from northern Sweden; iPSC, induced pluripotent stem cell.