Characterization of extracellular matrix components within mesenchymal stem cell spheroids preconditioned in either growth media or osteogenic media. (A, B): Picrosirius Red. (C, D): Fibronectin. (E, F): α2β1. Scale bar = 200 µm. Abbreviations: GM, growth media; OM, osteogenic media; PSR, Picrosirius Red.