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. 2016 Aug 24;11(8):e0160540. doi: 10.1371/journal.pone.0160540

Table 5. Characteristics of included studies on surgeons’ interactions with the device industry.

Study ID/ Sample size and funding Participants and settings Sampling frame and method Type of interaction Outcomes assessed
Khan, 2007[47] • N = 245
• Funding not reported
• Patients in the waiting area in orthopedic surgery clinic
• USA
• 51.0% female; average age: 55.5 (±14.5)
• Education: 33.9% collegegraduates; 19.2% graduate/postgraduates
• Frame: Patients in the waiting area in orthopedic surgery clinic
• Method: Convenient sampling
Surgeons as consultants for industry and medical device manufacturers • Attitudes towards the interactions
• Attitudes towards possible ways to manage the interactions
    -   Regulation of interaction
    -   Entities that should be involved in regulating interaction
Fisher, 2012[49] • N = 501
• Funding not reported
• North American public visiting the spineuniverse.com website
• USA; 2 weeks (date not reported)
• 63.3% females; 46.9% aged 30–49, 26.1% aged 50–59, and 19.2% aged 60 and above;
• Education: 52% tech or 4-year college; 25.7% graduate
• Frame: North American public visiting the spineuniverse.com website.
• Method: convenient sampling
Surgeon-industry COI relating to the role of surgeons in clinical research and the industry funding of such research • Beliefs about their effects on quality of care
• Attitudes towards the interactions
• Attitudes towards possible ways to manage the interactions
    -   Regulation of interaction
    -   Entities that should be involved in interaction
Camp, 2013[50] • N = 251 USA and N = 252 Canada
• No external funding sources
• Postoperative arthroplasty patients attending follow up hip and knee arthroplasty clinics
• USA & Canada; Nov 2010-March 2011
• 55% females US; 59% females Canada; age: 36% < 60, 64% 60 and above for US; 30% < 60, 69% 60 and above for Canada
• Education: US (51% college /university degree; Canada (51% college/university degree
• Frame: postoperative patients attending follow up hip and knee arthroplasty clinics at Mount Sinai Hospital and Holland Orthopaedic
• Method: Convenient sampling
Financial relationships with manufacturers (gifts, royalties, consultancy payments, speakers’ bureau presentations, or research support) • Awareness of the interactions of surgeons in general
• Beliefs about their effects on quality of care
• Attitudes towards the interactions
• Attitudes towards possible ways to manage the interactions
    -   Disclosure of interaction
    -   Regulation of interaction
    -   Entities that should be involved in regulation the interaction
Lieberman, 2013[48] • N = 100
• Funding from the NIH Musculoskeletal Transplant Foundation
• Patients (18 years old or older) scheduled for primary THA and TKA from the orthopedic practices of two joint arthroplasty specialists
• USA; September 2010 to September 2011
• 66% female; mean age (SD): 63 (±13.3)
• Education: 49% college; 20% Master’s or Doctoral degree
• Frame: All patients 18 years and older scheduled for primary THA and TKA from orthopedic practices of two joint arthroplasty specialists at an academic health center.
• Method: convenient sampling
• Developed prostheses
• Receives revenue from company
• Stock in company
• Receive future revenue
• Paid for product used in surgery
• Paid for product not used in surgery
• Awareness of the interactions of surgeons in general
• Attitudes towards the interactions
• Attitudes towards the effects of interactions on trust
• Attitudes towards possible ways to manage the interactions
    -   Disclosure of interaction
Dipaola, 2014[7] • N = 610
• Funding not reported
• North Americans representing the general public visiting the spineuniverse.com website
• USA; 2 weeks (no data)
• 63.3% females; 42.8% aged 30–49, 31% aged 50–59, 21% aged> 60
• Education: 54.8% technical school college; 24.6% graduate school
• Frame: visitors of the spineuniverse.com website.
• Method: convenient sampling
Surgeon-industry consulting relationships • Beliefs about their effects on quality of care
• Attitudes towards the interactions
• Attitudes towards possible ways to manage the interactions:
    -   Disclosure of interaction
    -   Entities that should be involved in regulating interaction